Alanine transaminase (ALT) is an enzyme found in the highest amounts in the liver. Injury to the liver results in release of the substance into the blood.
Alternate Names : SGPT, Serum glutamate pyruvate transaminase, Alanine transaminase
ALT is present in many different kinds of tissue in the body. However, it is highly concentrated in the liver. Therefore, when the liver is injured, ALT is released into the bloodstream.
Review Date: 02/22/2009
Reviewed By: David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine.
An increase in ALT levels may be due to:
Death of liver tissue (liver necrosis)
Hepatitis (viral, autoimmune)
Infectious mononucleosis ...
An increase in levels may be due to:
Cirrhosis (scarring of the liver)
Death of liver tissue (liver necrosis)
Lack of blood flow to the liver (liver ischemia)
Liver tumor or cancer
Medications that are toxic to the liver ...
Abbreviation: ' ALT '
Category: Common Medical Abbreviations
Meaning: Alanine Transaminase ...
See "Alanine aminotransferase"
1. In a trial, the alternative hypothesis might be that a treatment of unknown efficacy has more benefit than the standard treatment.
ALT (alanine aminotransferase): An enzyme normally present in liver and heart cells that is released into the bloodstream when the liver or heart is damaged from, for example, viral hepatitis or a heart attack).
(alanine aminotransferase) definition - Health and Medical Information produced by doctors - MedicineNet.com
alt.support.asthma FAQ: Asthma -- General information ...
ALT is an enzyme found mainly in liver cells, although smaller amounts are also in other organs of the body. When the liver becomes damaged, this enzyme leaks into the blood. A blood test can measure the level of ALT in the blood.
Alternative Diet Programs
American Heart Association Healthy Diet Guidelines ...
ALT is an enzyme that transfers an amino group from the amino acid alanine to a ketoacid acceptor (oxaloacetate). The enzyme was formerly called serum glutamic pyruvic transaminase (SGPT) after the products formed by this reaction.
relatively lower than AST in alcoholism
Assess severity/chronicity ...
ALT: see alanine aminotransferase.
ALTERNATIVE THERAPY: any type of treatment that is not considered standard or conventional practice in a given culture.
(SGPT) is, by contrast, normally found largely in the liver. This is not to say that it is exclusively located in liver, but that is where it is most concentrated. It is released into the bloodstream as the result of liver injury.
ALT is a form of outpatient adoptive immunotherapy utilizing autologous ex vivo activated T-cells accompanied by high dose cimetidine.
This section requires expansion.
(SGPT) must be performed at baseline and monitored at monthly intervals during the first six months then, if stable, every 6 to 8 weeks thereafter.
During ALT surgery, a laser makes tiny, evenly spaced burns in the trabecular meshwork. The laser does not create new drainage holes, but rather stimulates the drain to function more efficiently.
Spinal tap (lumbar puncture)'insertion of a needle between the lumbar vertebrae in the back to remove spinal fluid for testing
Liver biopsy 'removal of a sample of liver tissue for testing ...
The liver enzymes (ALT and AST) may be elevated in chronic hepatitis C infection. ALT in HCV is not correlated with disease progression or underlying histology. Many patients with chronic hepatitis C have normal ALT levels.
Alanine aminotransferase (). This enzyme, found in the liver, plays a role in metabolism, the process that converts food into energy. If the liver is injured, is released into the bloodstream.
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Alanine transaminase (). This is an enzyme that helps to process proteins. (An enzyme is a protein that helps to speed up chemical reactions. Various enzymes occur in the cells in the body.) Large amounts of occur in liver cells.
Liver function tests (AST, ALT, alkaline phosphatase, bilirubin), which detect liver damage or disease.
Alanine aminotransferase (), Dentins, Secondary, Diets, Chemically Defined, Diphyllobothriasis, Enterobacteria phage MS2, Erythroblastosis, Fetal, Habituation Spasm, Hemorrhagic Leukoencephalitides, Subacute, Hormone, Adrenocorticotropic, ...
Acute angle closure glaucoma, ALT, aqueous humor, argon laser trabeculoplasty, caffeine, canal of Schlemm, cataract, closed-angle glaucoma, congenital glaucoma, cornea, corticosteroid, diabetes, fluoroscein, glaucoma drainage device, ...
Elevation of liver enzymes (alkaline phosphatase, LDH, and ) suggests the presence of liver metastases. Elevated alkaline phosphatase and serum Ca may be the first evidence of bone metastases.
NASH is usually first suspected in a person who is found to have elevations in liver tests that are included in routine blood test panels, such as alanine aminotransferase (ALT) or aspartate aminotransferase (AST).
Normal Levels of AST and
Elevated Levels of AST and
Diseases That Cause Abnormal Aminotransferase Levels
Medications That Cause Abnormal Aminotransferase Levels
Less Common Causes of Abnormal Aminotransferase Levels ...
Tests: Blood tests of liver function show significantly elevated levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase, and bilirubin.
- a raised level of this enzyme is the best indicator of hepatitis as this enzyme is mainly found in the liver.
ALP - the levels of this enzyme are usually raised when the bile ducts are blocked.
Argon Laser Trabeculoplasty (ALT)
Argon laser trabeculoplasty (ALT) is the most common type of laser surgery. It is usually used to treat open angle glaucoma. During this procedure, you will sit facing the laser machine.
Definition The alanine aminotransferase test, also known as , is one of a group of tests known as liver function tests (or LFTs) and is used to monitor damage to the liver.
Baseline laboratory studies include bilirubin, AST, ALT, and prothrombin time (with INR). Studies are repeated at least daily.
Argon laser trabeculoplasty () may be the initial treatment for patients who do not respond to or who cannot tolerate drug therapy.
alanine transaminase (ALT) test
This test measures the level of alanine aminotransferase (an enzyme found predominantly in the liver) that is released into the bloodstream after acute liver cell damage.
In chronic hepatitis, the liver function tests show higher levels of the transaminases ( and AST) than the other liver enzymes. Hepatitis B and C tests, autoantibodies, copper and caeruloplasmin levels, and other tests are also necessary.
It is mentioned in the prescribing information that Arimidex can cause elevations in ALT, AST and bilirubin ...
Should I Be Drinking Artificial Sugars Such As Splenda?
passed in the breast milk to infants. Concerning...
This includes measuring the aminotransferases enzymes (AST and levels) ...
See also: Symptom, AST, Hepatitis, Liver disease, Jaundice